Products related to Discovery:
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Anticandidal Therapeutics : Discovery and Development
Developments of antifungal agents have declined as compared to other antibiotics that have displayed a potent development with time.There is an urgent need for both prophylactic and therapeutic treatments worldwide to control the severity of infections caused by Candida.Anticandidal Therapeutics: Discovery and Development provides the readers with a compiled knowledge of the fungal human infection Candida and the development of anticandidal drugs.Anticandidal Therapeutics helps researchers form the basis for the discovery and development of novel anticandidal therapies.In 14 chapters this book provides collective information on anticandidal agents and their discovery and development with respect to major drug transporter families, different stages of anticandidal agent development, recent trends and progress in antifungal translational research, clinical studies status of anticandidal therapeutic agents, and drug repurposing for development of novel anticandidal agents.
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Organization and Education Development : Reflecting and Transforming in a Self-Discovery Journey
Organization and Education Development combines reflective thinking and practice, action research living theory, and organization development to explore the self-discovery of meaning and purpose.It charts a journey undertaken by the author in pursuit of professional development through self-awareness and self-change as a fully integrated person and a better professor.This book is about an individual's integrative journey of self-discovery.The author’s narrative includes values and organizational development concepts and theories shared with fellow travelers, including supervisors, friends, and students.He shares invaluable insights and examples with the reader, using a model of a six-spoke wheel of final discovery and the MICAI intersection model.These integrative guides provide examples on how to search for what is best in everyday life and what gives us true meaning, encouraging personal reflection and ways of nurturing appreciation for our own lives.This multidisciplinary book combines western and eastern models and philosophies and draws from organization development, positive psychology, and education development.It will be ideal reading for students, researchers, and academics in the fields of organizational development, organizational psychology, social psychology, and education.It will appeal to any reader interested in learning about self-development.The Open Access version of this book, available at http://www.taylorfrancis.com, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license.
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Web-Scale Discovery Services : Principles, Applications, Discovery Tools and Development Hypotheses
Web-Scale Discovery Services: Principles, Applications, Discovery Tools and Development Hypotheses summarizes and presents the state-of-the-art in WSDS.The title promotes a middle-way between finding the best tool for each particular need and the search for the most reliable systems.The title identifies basic theoretical problems and offers practical solutions for librarians.The volume offers a summary of ideas from around the world, giving a new perspective that is backed up by strong theory.Offering a vision for libraries, this book also allows archivists, museum specialists, computer scientists, commercial operators and interested users to deepen their culture and information literacy. The great number of information sources now available and the changing habits of web users has led to the development of Web Scale Discovery Services (WSDS).The goal of these systems and techniques is to make catalogues, databases, institutional repositories, Open Access archives and other databases searchable and discoverable through a single point of access.The diffusion of systems and connections between data disseminated by libraries and published by other institutions poses a challenge to understanding discovery in the modern library.
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Trading and Price Discovery for Crude Oils : Growth and Development of International Oil Markets
This is a book about the international oil market. It takes a historical perspective on how the market emerged, developed, and became what it is today—the biggest commodity market in the world.It is mature and complex, but far from perfect. Throughout most of its 150-year history, the oil market has been monopolised by companies and governments.For only a fraction of that, oil traded in a relatively free market.As a result, we had to live with ‘big oil’, economic shocks, high oil prices, instability and wars.Using a simple concept of market power, this book will explain the meaning of ‘oil price’ and how it is established while offering a valuable lesson for other commodities. Market power is the key to understanding the ‘price of oil’.This book uses a simple concept of price-makers and price-takers to examine the evolution of oil markets, their structure, and prices.The early decades of the oil industry were competitive with low barriers to entry.Barely 25 years later, the Standard Oil company created a refining monopoly, buying oil at its own ‘posted’ price.In the following century, the cartel of major oil companies, helped by their governments, did the same at the international level.OPEC helped producing governments regain control of their own resources, but the organisation was never able to retain a similar level of control.After 1986 price collapse, OPEC abdicated the price-making function in favour of the market.While it never gave up attempts to influence prices, OPEC had to link their official prices to one of the global oil benchmarks. Modern international oil markets function because of oil benchmarks such as Brent, WTI and Dubai.This book showcases:• How oil traders played a prominent role in development of the industry• How policies of consuming nations helped oil cartels• Why and how the US price of oil was negative• How AI has changed the way markets operate and the way in which the markets are likely to change in futureThis book explores how oil markets grew, functioned, and have occasionally failed to do their job.The ecosystem of derivatives or ‘paper barrels’ trading in far greater volume than physical oil plays a very important role in mitigating risk.With this core tenant, setting the ‘price of oil’ is explained in detail.
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Is a year of self-discovery after completing education meaningful?
A year of self-discovery after completing education can be incredibly meaningful. It provides an opportunity to explore personal interests, passions, and goals without the pressure of academic deadlines and responsibilities. This time can be used to travel, volunteer, or pursue new hobbies, allowing for personal growth and a deeper understanding of oneself. It can also help in making more informed decisions about future career paths and life goals. Overall, a year of self-discovery can be a valuable and enriching experience that sets the stage for a fulfilling and purposeful life.
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What is an old discovery?
An old discovery refers to a scientific or historical finding that was made a significant amount of time ago. These discoveries have often stood the test of time and have had a lasting impact on our understanding of the world. Examples of old discoveries include the theory of evolution by Charles Darwin, the discovery of electricity by Benjamin Franklin, and the invention of the printing press by Johannes Gutenberg. These discoveries have shaped our modern world and continue to be studied and celebrated for their significance.
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What was Luther's great discovery?
Luther's great discovery was the concept of justification by faith alone. He believed that individuals could be saved by their faith in God alone, rather than through good works or the sacraments of the Catholic Church. This idea challenged the traditional teachings of the Church and sparked the Protestant Reformation. Luther's emphasis on faith as the key to salvation had a profound impact on Christianity and led to the formation of new Protestant denominations.
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Series like Star Trek: Discovery
Series like Star Trek: Discovery are typically science fiction shows that explore themes of space exploration, advanced technology, and diverse alien cultures. They often feature a diverse cast of characters and focus on moral and ethical dilemmas faced by the crew. These series also tend to have high production values, intricate storylines, and a mix of action and drama. Fans of Star Trek: Discovery may enjoy other similar shows like The Expanse, Battlestar Galactica, and Doctor Who.
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Basic Principles of Drug Discovery and Development
Basic Principles of Drug Discovery and Development presents the multifaceted process of identifying a new drug in the modern era, which requires a multidisciplinary team approach with input from medicinal chemists, biologists, pharmacologists, drug metabolism experts, toxicologists, clinicians, and a host of experts from numerous additional fields.Enabling technologies such as high throughput screening, structure-based drug design, molecular modeling, pharmaceutical profiling, and translational medicine are critical to the successful development of marketable therapeutics. Given the wide range of disciplines and techniques that are required for cutting edge drug discovery and development, a scientist must master their own fields as well as have a fundamental understanding of their collaborator’s fields.This book bridges the knowledge gaps that invariably lead to communication issues in a new scientist’s early career, providing a fundamental understanding of the various techniques and disciplines required for the multifaceted endeavor of drug research and development.It provides students, new industrial scientists, and academics with a basic understanding of the drug discovery and development process.The fully updated text provides an excellent overview of the process and includes chapters on important drug targets by class, in vitro screening methods, medicinal chemistry strategies in drug design, principles of in vivo pharmacokinetics and pharmacodynamics, animal models of disease states, clinical trial basics, and selected business aspects of the drug discovery process.
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Drug Discovery and Development : Technology in Transition
Essential insight into drug development and the pharmaceutical industry With unprecedented interest in the power that the modern therapeutic armamentarium has to combat disease, the new edition of Drug Discovery and Development is an essential resource for anyone interested in understanding how drugs and other therapeutic interventions are discovered and developed, through to clinical research, registration, and market access. The text has been thoroughly updated, with new information on biopharmaceuticals and vaccines as well as clinical development and target identification.Drug discovery and development continues to evolve rapidly and this new edition reflects important changes in the landscape. Edited by industry experts Raymond Hill and Duncan Richards, this market-leading text is suitable for undergraduates and graduates undertaking degrees in pharmacy, pharmacology, toxicology, and clinical development through to those embarking on a career in the pharmaceutical industry. Key stages of drug discovery and development Chapters outline the contribution of individual disciplines to the overall process Supplemented by specific chapters on different modalities Includes coverage of Oligonucleotide therapies; cell and gene therapy Now comes with online access on StudentConsult
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Neglected Tropical Diseases : Drug Discovery and Development
A drug discovery reference to the crippling tropical diseases that affect more than 1 billion people. Neglected Tropical Diseases is the first book of its kind to offer a guide that follows the World Health Organization?s list of neglected tropical diseases.The authors?all are experts on the topic?address the development of effective treatments for 12 crippling infectious diseases that affect almost 20% of the world?s popluation. The book includes information on the common approaches and the most important factors that lead to the development of new drugs for treating tropical diseases.Individual chapters review 12 neglected tropical diseases that are grouped by infectious agent, from viruses to bacteria to eukaryotic parasites.For each of these diseases, the book explains the unmet medical need and explores the current and potential drug discovery strategies.The book also includes information on potential drug compounds derived from natural products.This important book: -Ties together information from different sources for developing novel treatsments forneglected tropical diseases -Is aligned with WHO?s initiative to eradicate tropical diseases -Outlines current and potential drugs for treating tropical diseases -Provides a standard reference for the entire field Written for medicinal chemists, pharmaceutical chemists, pharmaceutical industry, virologists, parasitologists, and specialists on tropics medicine, Neglected Tropical Diseases offers an essential guide and a systematic reference for the development of successful treatments for 12 crippling infectious diseases.
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Contemporary Accounts in Drug Discovery and Development
CONTEMPORARY ACCOUNTS IN DRUG DISCOVERY AND DEVELOPMENT A useful guide for medicinal chemists and pharmaceutical scientists Drug discovery is a lengthy and complex process that typically involves identifying an unmet medical need, determining a biological target, chemical library screening to identify a lead, chemical optimization, preclinical studies and clinical trials.This process often takes many years to complete, and relies on practitioners’ knowledge of chemistry and biology, but also—and perhaps more importantly—on experience.Improving the success rate in discovery and development through a thorough knowledge of drug discovery principles and advances in technology is critical for advancement in the field.Contemporary Accounts in Drug Discovery and Development provides drug discovery scientists with the knowledge they need to quickly gain mastery of the drug discovery process.A thorough accounting is given for each drug covered within the book, as the authors provide pharmacology, drug metabolism, biology, drug development, and clinical studies for every case, with modern drug discovery principles and technologies incorporated throughout.Contemporary Accounts in Drug Discovery and Development readers will also find Case histories used as an engaging way of learning about the drug discovery/development processDetailed biological rational and background information, drug design principles, SAR development, ADMET considerations, and clinical studiesThe full history of individual marketed small molecule drugsCoverage of drug candidates that have passed Phase I clinical trials with different modalities, such as antibody drug conjugates (ADC), proteolysis-targeting chimera (PROTAC), and peptide drugsThe application of new technologies in drug discovery such as DNA-encoded libraries (DEL), positron emission tomography (PET), and physics-based computational modeling employing free energy perturbation (FEP) Contemporary Accounts in Drug Discovery and Development is a helpful tool for medicinal chemists, organic chemists, pharmacologists, and other scientists in drug research and process development.It may be considered essential reading for graduate courses in drug discovery, medicinal chemistry, drug synthesis, pharmaceutical science, and pharmacology.It is also a useful resource for pharmaceutical industry labs, as well as for libraries.
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What is your latest discovery?
My latest discovery is a new method for synthesizing a novel class of organic compounds with potential applications in drug development. By using a combination of computational modeling and organic synthesis techniques, my team and I were able to design and create these compounds with improved properties compared to existing ones. This discovery has the potential to open up new avenues for the development of more effective and targeted medications for various diseases.
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What was the gold discovery?
The gold discovery refers to the event in 1848 when gold was discovered at Sutter's Mill in California, sparking the California Gold Rush. The discovery led to a massive influx of people from all over the world seeking their fortunes in gold mining. This event had a significant impact on the development of California and the United States, as it led to rapid population growth and economic prosperity in the region.
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How can one continue to develop oneself and make progress in self-discovery?
One can continue to develop oneself and make progress in self-discovery by engaging in self-reflection and introspection. Setting aside time for self-care activities such as meditation, journaling, or seeking therapy can also aid in the process of self-discovery. Additionally, seeking out new experiences, learning new skills, and stepping out of one's comfort zone can help in gaining new perspectives and insights about oneself. Finally, surrounding oneself with supportive and encouraging individuals who can provide feedback and guidance can also contribute to personal growth and self-discovery.
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What kind of discovery is this?
This discovery is a significant scientific breakthrough in the field of astronomy. The detection of a new exoplanet, especially one that is potentially habitable, is a rare and exciting find. It opens up new possibilities for studying the potential for life beyond our solar system and deepens our understanding of the universe.
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